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Narayana V Sthanam

from Vestavia, AL
Age ~67

Narayana Sthanam Phones & Addresses

  • 3408 Surrey Hill Ln, Vestavia Hills, AL 35243 (205) 969-3474
  • Vestavia, AL
  • Hoover, AL
  • Birmingham, AL
  • 3408 Surrey Hill Ln, Vestavia, AL 35243 (205) 969-3474

Work

Company: Uab Position: Professor

Industries

Higher Education

Resumes

Resumes

Narayana Sthanam Photo 1

Professor At Uab

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Position:
Professor at UAB
Location:
Birmingham, Alabama Area
Industry:
Higher Education
Work:
UAB
Professor

Publications

Us Patents

Bioinformatic Method For Identifying Surface-Anchored Proteins From Gram-Positive Bacteria And Proteins Obtained Thereby

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US Patent:
7615616, Nov 10, 2009
Filed:
Sep 15, 2003
Appl. No.:
10/661809
Inventors:
Magnus Hook - Houston TX,
Yi Xu - Houston TX,
Jouko V. Sillanpaa - Houston TX,
Narayana Sthanam - Birmingham AL,
Karthe Ponnuraj - Birmingham AL,
Joseph M. Patti - Cumming GA,
Jeff T. Hutchins - Cumming GA,
Andrea Hall - Acworth GA,
Maria G. Bowden - Sugarland TX,
Assignee:
The Texas A&M University System - College Station TX
Inhibitex, Inc. - Alpharetta GA
The UAB Research Foundation - Birmingham AL
International Classification:
C07K 16/00
US Classification:
5303871, 5303881, 4241301, 4241331, 4241391, 4241411, 4241501, 4241641, 435243, 435975
Abstract:
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as and bacteria, which can then be utilized in methods to prevent and treat infections caused by Gram-positive bacteria. The method involves identifying from sequence information those proteins with a putative C-terminal LPXTG (SEQ ID NO:1) cell wall sorting signal and other structural similarities to MSCRAMM® proteins having the LPXTG-anchored cell wall proteins. The MSCRAMM® proteins and immunogenic regions therein that are identified and isolated using the present invention may be used to generate antibodies useful in the diagnosis, treatment or prevention of Gram positive bacterial infections.

Bioinformatic Method For Identifying Surface-Anchored Proteins From Gram-Positive Bacteria And Proteins Obtained Thereby

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US Patent:
7850974, Dec 14, 2010
Filed:
Oct 8, 2009
Appl. No.:
12/575909
Inventors:
Magnus Hook - Houston TX,
Yi Xu - Houston TX,
Jouko V. Sillanpaa - Houston TX,
Narayana Sthanam - Birmingham AL,
Karthe Ponnuraj - Birmingham AL,
Joseph M. Patti - Cumming GA,
Jeff T. Hutchins - Cumming GA,
Andrea Hall - Acworth GA,
Maria G. Bowden - Sugarland TX,
Assignee:
The Texas A&M University System - College Station TX
Inhibitex, Inc. - Alpharetta GA
The UAB Research Foundation - Birmingham AL
International Classification:
A61K 39/02
US Classification:
4241901, 4241851, 4242341
Abstract:
A bioinformatic method for identifying and isolating proteins and peptides with MSCRAMM®-like characteristics from Gram positive bacteria, such as and bacteria, and proteins and peptides obtained thereby are provided which can be utilized in methods to prevent and treat infections caused by Gram-positive bacteria. The method involves identifying from sequence information those proteins with a putative C-terminal LPXTG (SEQ ID NO:1) cell wall sorting signal and other structural similarities to MSCRAMM® proteins having the LPXTG-anchored cell wall proteins. The MSCRAMM® proteins and immunogenic regions therein that are identified and isolated using the present invention may be useful in the diagnosis, treatment or prevention of Gram positive bacterial infections.

Collagen Binding Protein Compositions And Methods Of Use

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US Patent:
6288214, Sep 11, 2001
Filed:
May 14, 1997
Appl. No.:
8/856253
Inventors:
Magnus Hook - Houston TX
Joseph M. Patti - Missouri City TX
Narayana Sthanam - Vestavia AL
Jindrich Symersky - Birmingham AL
Assignee:
Texas A&M University Systems - College Station TX
International Classification:
C07K 1600
C12P 2108
A61K 39395
A61K 3940
US Classification:
5303871
Abstract:
Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of use. The CBP protein and antigenic epitopes derived therefrom are contemplated for use in the treatment of pathological infections, and in particular, for use in the prevention of bacterial adhesion to Col. DNA segments encoding these proteins and anti-(Col binding protein) antibodies will also be of use in various screening, diagnostic and therapeutic applications including active and passive immunization and methods for the prevention of bacterial colonization in an animal such as a human. These DNA segments and the peptides derived therefrom are contemplated for use in the preparation of vaccines and, also, for use as carrier proteins in vaccine formulations, and in the formulation of compositions for use in the prevention of S. aureus infection.
Narayana V Sthanam from Vestavia, AL, age ~67 Get Report